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1.
Gan To Kagaku Ryoho ; 50(1): 102-104, 2023 Jan.
Artículo en Japonés | MEDLINE | ID: mdl-36760000

RESUMEN

An 83-year-old woman developed jaundice, and was diagnosed as perihilar cholangiocarcinoma. Abdominal contrast- enhanced CT revealed coexisting portosystemic shunt between portal vein and inferior vena cava, however, her blood ammonia level was normal. She underwent right hemihepatectomy and caudate lobectomy combined with extrahepatic bile duct resection and portal vein resection. Postoperatively, hyperammonemia refractory to conservative treatment was observed. The blood ammonia level increased to 180µg/dL and she was suffered from grade Ⅲ hepatic encephalopathy on the 20th postoperative day. CT showed an increase in the diameter of the portosystemic shunt, while there was only a slight increase in the remnant left lobe of the liver. These findings indicated that hepatic encephalopathy was caused by increased portosystemic shunt blood flow and decreased portal venous flow. Hepatic encephalopathy was rapidly improved by percutaneous transhepatic portosystemic shunt obliteration.


Asunto(s)
Neoplasias de los Conductos Biliares , Encefalopatía Hepática , Tumor de Klatskin , Derivación Portosistémica Intrahepática Transyugular , Humanos , Femenino , Anciano de 80 o más Años , Tumor de Klatskin/complicaciones , Encefalopatía Hepática/etiología , Encefalopatía Hepática/terapia , Amoníaco , Derivación Portosistémica Intrahepática Transyugular/efectos adversos , Neoplasias de los Conductos Biliares/complicaciones , Neoplasias de los Conductos Biliares/cirugía , Neoplasias de los Conductos Biliares/patología
2.
Gan To Kagaku Ryoho ; 50(13): 1825-1827, 2023 Dec.
Artículo en Japonés | MEDLINE | ID: mdl-38303220

RESUMEN

The patient was a 90-year-old man. He was referred to our department with a diagnosis of ascending colon cancer after lower gastrointestinal endoscopy for a positive stool occult blood test. Lower gastrointestinal endoscopy revealed a type 1 tumor 30 mm in the ascending colon and a type 3 tumor 50 mm in the cecum. Biopsy revealed Group 5(tub1)for the ascending colon lesion, but Group 2 for the cecum lesion. The patient was clinically diagnosed as having overlapping ascending colon cancer and cecum cancer, and a right hemicolectomy of the colon was performed. Histopathological examination revealed ascending colon cancer and primary malignant lymphoma of the cecum.


Asunto(s)
Neoplasias del Colon , Linfoma , Masculino , Humanos , Anciano de 80 o más Años , Colon Ascendente/cirugía , Colon Ascendente/patología , Neoplasias del Colon/cirugía , Neoplasias del Colon/patología , Ciego/cirugía , Biopsia
3.
Gan To Kagaku Ryoho ; 50(13): 1909-1911, 2023 Dec.
Artículo en Japonés | MEDLINE | ID: mdl-38303249

RESUMEN

A 58-year-old man with chronic renal disease underwent ileo-cecal resection with lymph node dissection for cancer of the ascending colon at his previous physician. The pathological diagnosis was pT3N0M0, pStage Ⅱa. One year and 7 months after surgery, he was diagnosed with local and lymph node recurrence and referred to our department. Contrast- enhanced CT revealed that an irregular nodal shadow 25 mm in size adjacent to the superior mesenteric artery and the transvers part of duodenum, which was suspicious for lymph node recurrence. We regarded this patient as marginally resectable and neoadjuvant treatment was considered, but because the patient was on dialysis, we decided to operate without pre-operative treatment. Surgical findings showed invasion of a recurrent lymph node into a primary branch of the superior mesenteric artery and vein. We temporarily blocked these vessels and cut off these vessels after checking that blood flow in the intestine was maintained by intravenous injection of ICG. The lymph node was also invading the uncinate process of the pancreas and the transvers part of duodenum, we performed partial resection of those organs. Pathology revealed no tumor exposure on the dissected surface and R0 resection was achieved. The patient received 5 courses of postoperative folinate/ uracil/tegafur therapy and is alive 1 year postoperatively without recurrence.


Asunto(s)
Colon Ascendente , Neoplasias del Colon , Masculino , Humanos , Persona de Mediana Edad , Colon Ascendente/patología , Arteria Mesentérica Superior , Neoplasias del Colon/cirugía , Neoplasias del Colon/patología , Ganglios Linfáticos/patología , Escisión del Ganglio Linfático , Diálisis Renal
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